International Journal of Evidence-Based Medicine is an international, open-access, peer-reviewed journal dedicated to advancing healthcare by publishing the highest quality evidence syntheses and methodological research.

We invite researchers, clinicians, systematic reviewers, and policymakers to submit their work to a journal committed to methodological rigor and clinical relevance. We are dedicated to disseminating innovative research that helps practitioners interpret and apply medical evidence to improve patient outcomes and healthcare delivery worldwide.

We seek submissions that address the critical appraisal of medical literature, evidence synthesis, translation of research into practice, and the impact of evidence on health systems.

Priority Topics Include:

Systematic Reviews & Meta-Analyses
Evidence-Based Clinical Guidelines
Comparative Effectiveness Research
Bias Assessment & Research Methodology
Real-World Evidence and Big Data Applications

CURRENT ISSUE

Volume 1, Issue 1, 2026

(Ongoing)

Original Article

Ultrasound-Guided Versus Fluoroscopic Conservative Reduction of Intestinal Intussusception in Children: A Retrospective Comparative Study

Jamshid Shamsiev, Amine Ksia, Azamat Shamsiev, Kenan Karavdic, Mahmoud El Fiky

International Journal of Evidence-Based Medicine, 1(1), 2026, jebm001, https://doi.org/10.63946/jebm/18437

ABSTRACT: Introduction: Intestinal intussusception is the most common form of acquired intestinal obstruction in childhood. Diagnostic errors reach 50%, and complications occur in up to 53.7% of cases. Pneumoirrigoscopy under fluoroscopic control (PIS) has been the standard conservative technique, but its radiation burden and single-attempt limitation prompted the development of ultrasound-guided hydroechocolonographic disinvagination (HEC). This study aimed to compare the clinical outcomes of HEC and PIS in paediatric intestinal intussusception.
Methods: A retrospective comparative study of 132 children aged 2 months to 10 years treated at the Specialized Paediatric Surgical Clinic of Samarkand State Medical University between 2000 and 2023. The control group (CG, n=59; January 2000–December 2013) received conventional PIS; the study group (SG, n=73; January 2014–December 2023) underwent ultrasound-guided HEC, a radiation-free technique developed at our institution. Primary outcomes were the rate of successful conservative reduction (assessed per patient), length of hospital stay, and mortality. Chi-squared and Student’s t-tests were used; p<0.05 was considered significant.
Results: The predominant age group was 6 months to 1 year (51.5%); males predominated (70.5%, p<0.001). The ileocaecal variant was found in 90.1% of patients. Successful conservative reduction was achieved in 53.4% (39/73) of the study group versus 39.0% (23/59) in the control group. Mean hospital stay was significantly shorter in the study group (2.5±0.66 vs 4.6±0.51 days, p<0.05). Group-specific mortality was 2.7% (2/73) in the SG versus 8.5% (5/59) in the CG.
Conclusion: Ultrasound-guided HEC is a safe, effective, and radiation-free alternative to PIS, achieving a higher rate of conservative reduction, a significantly shorter hospital stay, and enabling multiple reduction attempts. Disease duration alone should not determine treatment modality; clinical condition and the absence of peritoneal signs must be considered jointly.